Aubry, Evelyne M.; Raio, Luigi; Oelhafen, Stephan (2021). Effect of the IADPSG screening strategy for gestational diabetes on perinatal outcomes in Switzerland Diabetes Research and Clinical Practice, 175, p. 108830. Elsevier 10.1016/j.diabres.2021.108830
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Aims: To evaluate the impact adoption of the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria on prevalence of gestational diabetes mellitus (GDM) and risks of perinatal outcomes. Methods: Retrospectively, 155,103 women screened with selective two step criteria in Switzerland in period 1 (2005–2010) were compared to 170,427 women screened with IADPSG criteria in period 2 (2012–2017). GDM prevalence over time was established and multivariable regression used to assess variation in risks for GDM related events and perinatal outcomes. Results: GDM prevalence increased steadily over both study periods from 1.8% to 9.0%. A risk reduction of GDM-related events was shown only for women with one or two risk factors for GDM present (relative risk (95% confidence interval)): (0.93 (0.90,0.97), 0.90 (0.83,0.96)). The comparison of perinatal outcomes between the two study periods revealed a significant lower risk for newborns large for gestational age (LGA) (0.93 (0.91–0.95)), preterm delivery (0.94 (0.92–0.97)) and neonatal hypoglycemia (0.83 (0.77–0.90)) in period 2. Conclusion: The introduction of the IADPSG criteria for the screening of GDM increased prevalence by threefold with no substantial improvements in GDM related events for women without risk factors but reduced the risks for LGA, neonatal hypoglycemia and preterm birth.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
School of Health Professions School of Health Professions > Midwifery |
Name: |
Aubry, Evelyne M. 0000-0002-3861-0694; Raio, Luigi and Oelhafen, Stephan 0000-0002-4238-6728 |
Subjects: |
R Medicine > RG Gynecology and obstetrics |
ISSN: |
1872-8227 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Jean Anthony Grand-Guillaume-Perrenoud |
Date Deposited: |
03 Aug 2021 15:12 |
Last Modified: |
08 Aug 2021 01:34 |
Publisher DOI: |
10.1016/j.diabres.2021.108830 |
Uncontrolled Keywords: |
Gestational diabetes mellitus, International Association of the Diabetes and Pregnancy Study Groups, Perinatal outcomes, Prevalence |
ARBOR DOI: |
10.24451/arbor.15231 |
URI: |
https://arbor.bfh.ch/id/eprint/15231 |
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