Impact of milk processing on the generation of peptides during digestion

Kopf, Katrin Annika; Schwander, Flurina; Gijs, Martin; Vergères, Guy; Portmann, Reto; Egger, Lotti (2014). Impact of milk processing on the generation of peptides during digestion International Dairy Journal, 35(2), pp. 130-138. Elsevier 10.1016/j.idairyj.2013.10.012

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Milk processing may induce changes in dairy product composition and influence digestibility and nutrient bioavailability. Differences in protein degradation and peptide generation were studied for β-lactoglobulin and αS1-casein from commercially available dairy products before, during, and after in vitro digestion. All major milk proteins, except β-lactoglobulin, were degraded to smaller peptides during the gastric phase in all investigated products. After the gastric phase, a shortened fragment of β-lactoglobulin was identified in the non-fermented dairy products, underlining differences in protein conformation due to the fermentation process. During the gastric phase, greater numbers of small peptides were generated from αS1-casein than from β-lactoglobulin. The monitoring of generation of specific β-lactoglobulin and αS1-casein peptide profiles by liquid chromatography–mass spectrometry allowed the identification of potential bioactive peptides. Peptides with satiety-influencing DPP-4 inhibiting properties were monitored and quantities were compared between products to identify promising targets for the development of new health promoting products.

Item Type:	Journal Article (Original Article)
Division/Institute:	School of Agricultural, Forest and Food Sciences HAFL > Consumer-focused Food Production
Name:	Kopf, Katrin Annika0000-0002-7443-7489; Schwander, Flurina; Gijs, Martin; Vergères, Guy; Portmann, Reto and Egger, Lotti
Subjects:	T Technology > T Technology (General)
ISSN:	09586946
Publisher:	Elsevier
Language:	English
Submitter:	Katrin Annika Kopf
Date Deposited:	17 Dec 2019 10:08
Last Modified:	18 Dec 2020 13:29
Publisher DOI:	10.1016/j.idairyj.2013.10.012
ARBOR DOI:	10.24451/arbor.9256
URI:	https://arbor.bfh.ch/id/eprint/9256