Evaluation of HOXC8 in crested Swiss chicken

Joller, S.; Ammann, P.; Flury, Christine; Drögemüller, C. (2018). Evaluation of HOXC8 in crested Swiss chicken Animal Genetics, 49(4), pp. 334-336. Wiley 10.1111/age.12674

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The crest in chicken consists of elongated and upraised feathers, as seen in various breeds such as the Silkie chicken. Recently, the still unknown causative mutation for the crest phenotype was assigned to chromosome 33 and an ectopic expression of HOXC8 was shown. The aim this study was to evaluate whether the crest phenotype in a local Swiss chicken breed, the Appenzeller Spitzhaubenhuhn, is associated with HOXC8. Three previously reported crest‐associated flanking markers at the HOXC8 locus were genotyped in cohorts of this breed and two other local breeds without the crest phenotype. For the Appenzeller Spitzhaubenhuhn chicken showing the crest phenotype, no clear association of the reported markers could be revealed. Furthermore, the two exons of HOXC8 were sequenced in crested chicken of the Appenzeller Spitzhaubenhuhn and Silkie breeds and revealed no evidence of polymorphisms within the coding region of HOXC8. Therefore, the molecular genetic etiology for the crest phenotype in the investigated breeds remains unclear.

Item Type:	Journal Article (Original Article)
Division/Institute:	School of Agricultural, Forest and Food Sciences HAFL > Resource-efficient agricultural production systems School of Agricultural, Forest and Food Sciences HAFL > Agriculture
Name:	Joller, S.; Ammann, P.; Flury, Christine and Drögemüller, C.
Subjects:	Q Science > QL Zoology S Agriculture > SF Animal culture
ISSN:	02689146
Publisher:	Wiley
Language:	English
Submitter:	David Zimmer
Date Deposited:	17 Sep 2019 11:02
Last Modified:	17 Sep 2019 11:02
Publisher DOI:	10.1111/age.12674
Uncontrolled Keywords:	Appenzeller Spitzhaubenhuhn, bird, feathers, homeobox, Silkie chicken
ARBOR DOI:	10.24451/arbor.8139
URI:	https://arbor.bfh.ch/id/eprint/8139