Schurz, Alexander Philipp; Walter, Matthias M.; Liechti, Melanie Nadia; Clijsen, Ron; Deliens, Tom; Taeymans, Jan; Lutz, Nathanael (2024). Health economic evaluation of weight reduction interventions in individuals suffering from overweight or obesity and a musculoskeletal diagnosis—a systematic review BMC Musculoskeletal Disorders, 25(1) BioMed Central 10.1186/s12891-024-07861-9
|
Text
Schurz et al. 2024 BMC MSK DO.pdf - Published Version Available under License Creative Commons: Attribution-Noncommercial-No Derivative Works (CC-BY-NC-ND). Download (1MB) | Preview |
Background Most of the worldwide population is overweight and suffers from the resulting musculoskeletal comorbidities such as knee osteoarthritis or back pain. Practice guidelines recommend weight loss interventions for individuals suffering from these conditions. This systematic review investigated whether including a weight loss intervention in the musculoskeletal therapy of these individuals was cost-effective compared to administering the musculoskeletal therapy alone. Methods This study followed the PRISMA guidelines to systematically and independently search six databases and select full health economic evaluations published up to May 2024 from health care or societal perspectives according to predefined eligibility criteria. Cost data were standardised to 2023 Belgium Euros. The methodological quality was assessed using two health economic-specific checklists. Results The searches produced 5′305 references, of which 8 studies were selected for a total of 1′726 participants. The interventions consisted of different exercise plans and nutritional targets. Six values were in the north-eastern; leading to increased quality-adjusted life year (QALY) and higher costs; and two in the south-eastern quadrant of the cost-utility plane; leading to increased QALYs and lower costs. Two studies observed no differences in QALYs. Incremental cost utility ratios (ICUR) ranged from €13′580.10 to €34′412.40 per additional QALY from a healthcare perspective. From a societal perspective, the ICUR was €30′274.84. The included studies fulfilled 86 percent of the criteria in trial-based economic evaluations and 57 percent in model-based economic evaluations. The most common limitations of the studies were related to appropriate cost measures’ specifications, research questions, time horizon choices, and sensitivity analyses. Conclusions This systematic review showed weak but consistent evidence of cost-effectiveness for adding a weight loss intervention to musculoskeletal therapy for individuals with overweight, from either perspective. Further economic evaluations should evaluate the long-term cost-effectiveness of the intervention.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
School of Health Professions School of Health Professions > Physiotherapy School of Health Professions > Physiotherapy > Public Health & Physiotherapy Related Health Economics |
Name: |
Schurz, Alexander Philipp 0000-0002-2818-0782; Walter, Matthias M.; Liechti, Melanie Nadia 0000-0003-4447-2379; Clijsen, Ron 0000-0001-7125-5332; Deliens, Tom; Taeymans, Jan and Lutz, Nathanael 0000-0002-7512-7060 |
ISSN: |
1471-2474 |
Publisher: |
BioMed Central |
Language: |
English |
Submitter: |
Alexander Philipp Schurz |
Date Deposited: |
07 Oct 2024 11:43 |
Last Modified: |
07 Oct 2024 11:43 |
Publisher DOI: |
10.1186/s12891-024-07861-9 |
ARBOR DOI: |
10.24451/arbor.22585 |
URI: |
https://arbor.bfh.ch/id/eprint/22585 |
Actions (login required)
 |
View Item |