Salzmann, Simon Adrian; Wakili, Philip; Al-Nawaiseh, Sami; Považay, Boris; Meier, Christoph; Burri, Christian (2023). High-Precision Optical Coherence Tomography Navigated Laser Retinopexy for Retinal Breaks Life, 13(5), p. 1145. MDPI 10.3390/life13051145
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The prevalent cause of retinal detachment is a full-thickness retinal break and the ingress of fluid into the subretinal space. To prevent progression of the detachment, laser photocoagulation (LPC) lesions are placed around the break in clinical practice to seal the tissue. Unlike the usual application under indirect ophthalmoscopy, we developed a semi-automatic treatment planning software based on a sequence of optical coherence tomography (OCT) scans to perform navigated LPC treatment. The depth information allows demarcation of the border where the neurosensory retina is still attached to the retinal pigment epithelium (RPE), which is critical for prevention of detachment progression. To evaluate the method, artificially provoked retinal breaks were treated in seven ex-vivo porcine eyes. Treatment outcome was assessed by fundus photography and OCT imaging. The automatically applied lesions surrounding each detachment (4.4–39.6 mm2) could be identified as highly scattering coagulation regions in color fundus photography and OCT. Between the planned and applied pattern, a mean offset of 68 µm (SD ± 16.5 µm) and a mean lesion spacing error of 5 µm (SD ± 10 µm) was achieved. The results demonstrate the potential of navigated OCT-guided laser retinopexy to improve overall treatment accuracy, efficiency, and safety.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
School of Engineering and Computer Science > Institute for Human Centered Engineering (HUCE) > HUCE / Laboratory for Optics School of Engineering and Computer Science |
Name: |
Salzmann, Simon Adrian 0000-0001-5453-8808; Wakili, Philip; Al-Nawaiseh, Sami; Považay, Boris; Meier, Christoph and Burri, Christian 0000-0003-2690-7527 |
Subjects: |
R Medicine > RE Ophthalmology |
ISSN: |
2075-1729 |
Publisher: |
MDPI |
Language: |
English |
Submitter: |
Simon Adrian Salzmann |
Date Deposited: |
17 May 2023 09:41 |
Last Modified: |
17 May 2023 09:41 |
Publisher DOI: |
10.3390/life13051145 |
Uncontrolled Keywords: |
OCT; guided laser; photocoagulation; LPC; retinal detachment prophylaxis; retinal tear |
ARBOR DOI: |
10.24451/arbor.19230 |
URI: |
https://arbor.bfh.ch/id/eprint/19230 |
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