Distress regulates different pathways in the brain of common carp: an initial study

Burren, Alexander; Pietsch, Constanze (2021). Distress regulates different pathways in the brain of common carp: an initial study Animals, 11(2), pp. 1-16. MDPI 10.3390/ani11020585

Preview	Text Pilot-Trial-Paper-Dez-2020.pdf - Submitted Version Available under License Creative Commons: Attribution (CC-BY). Download (1MB) | Preview
Preview	Text animals-11-00585-v2.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (2MB) | Preview

For the present study, a stress trial with common carp, which is one of the most important species in aquaculture world-wide, was conducted to identify relevant gene regulation pathways in different areas of the brain. Acute distress by air exposure significantly activated the expression of the immediate early gene c-fos in the telencephalon. In addition, evidence for regulation of the two crf genes in relation to their binding protein (crh-bp) have been highlighted in this initial study. Inference about the effects of distress by air exposure has been obtained by using point estimation which allows the prediction of a single value that is the best description of the up to know mostly unknown effects of stress in different brain regions of carp. Furthermore, principal component analyses have been performed to reveal possible regulation patterns in the different parts of the fish brain. In conclusion, these initial studies on gene regulation in the carp brain influenced by exposure to a stressor reveal that a number of genes may be successfully used as markers for exposure to unfavourable conditions.

Item Type:	Journal Article (Original Article)
Division/Institute:	School of Agricultural, Forest and Food Sciences HAFL School of Agricultural, Forest and Food Sciences HAFL > Agriculture School of Agricultural, Forest and Food Sciences HAFL > Agriculture > Livestock and Horses
Name:	Burren, Alexander0000-0001-9948-7039 and Pietsch, Constanze0000-0002-3572-8945
Subjects:	S Agriculture > SH Aquaculture. Fisheries. Angling
ISSN:	2076-2615
Publisher:	MDPI
Language:	English
Submitter:	Heidi Signer-Hasler
Date Deposited:	21 Dec 2020 09:51
Last Modified:	06 Mar 2021 19:44
Publisher DOI:	10.3390/ani11020585
Uncontrolled Keywords:	aquaculture; stressors; carp; early immediate genes; biostatistics
ARBOR DOI:	10.24451/arbor.13819
URI:	https://arbor.bfh.ch/id/eprint/13819