Comparison of equations for estimating resting metabolic rate in healthy subjects over 70 years of age

Melzer, Katarina; Laurie Karsegard, Véronique; Genton, Laurence; Kossovsky, Michel P; Kayser, Bengt; Pichard, Claude (2007). Comparison of equations for estimating resting metabolic rate in healthy subjects over 70 years of age Clinical Nutrition, 26(4), pp. 498-505. Elsevier 10.1016/j.clnu.2007.05.002

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There is a lack of validation studies of formulas for estimating resting metabolic rate (RMR) in healthy subjects over 70 years of age. Indirect calorimetry allows measuring RMR (RMRm), but is time consuming and costly and therefore formula are generally used to estimate RMR (RMRe). We assessed the degree of agreement between RMRm and RMRe predicted by five popular equations: Harris-Benedict (HB), Mifflin-St Jeor (MJ), Owen (OW), World Health Organization (WHO/FAO/UNU) and Lührmann (LM) in a cohort of elderly subjects.; In 119 healthy subjects, aged 70-98 yr, RMRm was obtained by indirect calorimetry and RMRe by the HB, MJ, OW, WHO/FAO/UNU and LM equations. Means were compared by paired t-test. The Bland and Altman method was used to assess agreement between RMRm and RMRe. Accuracy was defined as the % of individuals whose RMRe was within +/-10% of RMRm.; The HB showed the lowest mean RMRe-RMRm difference (-40.9 kcal/day), followed by LM (+44.8 kcal/day) and WHO/FAO/UNU (+53 kcal/day). The HB performed the best of the five equations, having 72.4% of the cases within+/-10% of RMRm. In 18.7% of male subjects and 20% of female subjects HB underestimated the measured values.; Large discrepancies exist between RMRm and RMRe in subjects above 70 years of age. HB performs best, but still tends to underestimate in both sexes. In order to develop more accurate equations to estimate RMR in elderly subjects it would be worthwhile to examine whether additionally specific markers of body composition should be taken into consideration.

Item Type:	Journal Article (Original Article)
Division/Institute:	Swiss Federal Institute of Sports Magglingen SFISM > EHSM - Leistungssport
Name:	Melzer, Katarina; Laurie Karsegard, Véronique; Genton, Laurence; Kossovsky, Michel P; Kayser, Bengt and Pichard, Claude
ISSN:	0261-5614 (Print) 1532-1983 (Online)
Publisher:	Elsevier
Language:	English
Submitter:	Service Account
Date Deposited:	03 Mar 2021 12:00
Last Modified:	30 Sep 2021 02:17
Publisher DOI:	10.1016/j.clnu.2007.05.002
PubMed ID:	17583391
Uncontrolled Keywords:	Resting metabolic Rate Predictive equations Healthy elderly subjects
ARBOR DOI:	10.24451/arbor.11165
URI:	https://arbor.bfh.ch/id/eprint/11165