Similar Hemoglobin Mass Response in Hypobaric and Normobaric Hypoxia in Athletes

Hauser, Anna; Schmitt, Laurent; Trösch, Severin; Saugy, Jonas J.; Cejuela-Anta, Roberto; Faiss, Raphael; Robinson, Neil; Wehrlin, Jon Peter; Millet, Grégoire P. (2016). Similar Hemoglobin Mass Response in Hypobaric and Normobaric Hypoxia in Athletes Medicine & Science in Sports & Exercise, 48(4), pp. 734-741. Lippincott Williams & Wilkins 10.1249/MSS.0000000000000808

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Purpose: To compare hemoglobin mass (Hb(mass)) changes during an 18-d live high-train low (LHTL) altitude training camp in normobaric hypoxia (NH) and hypobaric hypoxia (HH). Methods: Twenty-eight well-trained male triathletes were split into three groups (NH: n = 10, HH: n = 11, control [CON]: n = 7) and participated in an 18-d LHTL camp. NH and HH slept at 2250 m, whereas CON slept, and all groups trained at altitudes <1200 m. Hb(mass) was measured in duplicate with the optimized carbon monoxide rebreathing method before (pre-), immediately after (post-) (hypoxic dose: 316 vs 238 h for HH and NH), and at day 13 in HH (230 h, hypoxic dose matched to 18-d NH). Running (3-km run) and cycling (incremental cycling test) performances were measured pre and post. Results: Hb(mass) increased similar in HH (+4.4%, P < 0.001 at day 13; +4.5%, P < 0.001 at day 18) and NH (+4.1%, P < 0.001) compared with CON (+1.9%, P = 0.08). There was a wide variability in individual Hb(mass) responses in HH (-0.1% to +10.6%) and NH (-1.4% to +7.7%). Postrunning time decreased in HH (-3.9%, P < 0.001), NH (-3.3%, P < 0.001), and CON (-2.1%, P = 0.03), whereas cycling performance changed nonsignificantly in HH and NH (+2.4%, P > 0.08) and remained unchanged in CON (+0.2%, P = 0.89). Conclusion: HH and NH evoked similar Hb(mass) increases for the same hypoxic dose and after 18-d LHTL. The wide variability in individual Hb(mass) responses in HH and NH emphasizes the importance of individual Hb(mass) evaluation of altitude training.

Item Type:	Journal Article (Original Article)
Division/Institute:	Swiss Federal Institute of Sports Magglingen SFISM > EHSM - Leistungssport > Sportphysiologie Ausdauer
Name:	Hauser, Anna; Schmitt, Laurent; Trösch, Severin; Saugy, Jonas J.; Cejuela-Anta, Roberto; Faiss, Raphael; Robinson, Neil; Wehrlin, Jon Peter and Millet, Grégoire P.
ISSN:	0195-9131 (Print) 1530-0315 (Online)
Publisher:	Lippincott Williams & Wilkins
Language:	English
Submitter:	Service Account
Date Deposited:	24 Feb 2021 12:32
Last Modified:	02 Oct 2021 02:18
Publisher DOI:	10.1249/MSS.0000000000000808
PubMed ID:	26540262
Uncontrolled Keywords:	Altitude training Live high-train low Simulated altitude Performance Endurance athletes Individual reponse
ARBOR DOI:	10.24451/arbor.10942
URI:	https://arbor.bfh.ch/id/eprint/10942